NSABP Members' Area Password Protected - Access Limited to NSABP Participating Institutions Only NSABP Foundation, Inc. General NSABP Information Financial Conflicts of Interest Policy Contact the NSABP Employment Clinical Trials Information Clinical Trials Overview Protocol Chart Never Say Lost Treatment Trials Information Protocol B-51 Protocol B-52 Protocol B-53/S1207 Protocol B-55/BIG 6-13 Prevention Trials Information Protocol P-1 - BCPT Protocol P-2 - STAR To report problems, ask questions or make comments, please send e-mail to: Webmaster@nsabp.pitt.edu |
Protocol B-16 A Three-Arm Clinical Trial Comparing Tamoxifen Alone with L-PAM, 5-FU, Adriamycin and Tamoxifen or with Short, Intensive Adriamycin-Cyclophosphamide and Tamoxifen in Positive-Node Patients Having the Following Age and Receptor Criteria: 50-59 Years - PR = 10 fmol or more, regardless of ER 60-70 Years - All Patients Specific Aims To determine, in patients with histologically positive axillary nodes who are classified as tamoxifen-responsive, whether tamoxifen alone is as effective as (1) PAF + tamoxifen, or (2) short-course, intensive chemotherapy with AC + tamoxifen, with respect to disease-free survival and survival. The efficacy of ACT relative to PAFT will also be evaluated. |