NSABP Members' Area Password Protected - Access Limited to NSABP Participating Institutions Only NSABP Foundation, Inc. General NSABP Information Financial Conflicts of Interest Policy Contact the NSABP Employment Clinical Trials Information Clinical Trials Overview Protocol Chart Never Say Lost Treatment Trials Information Protocol B-51 Protocol B-52 Protocol B-53/S1207 Protocol B-55/BIG 6-13 Prevention Trials Information Protocol P-1 - BCPT Protocol P-2 - STAR To report problems, ask questions or make comments, please send e-mail to: Webmaster@nsabp.pitt.edu |
Protocol B-19 A Clinical Trial to Compare Sequential Methotrexate, 5-Fluorouracil (M→F) with Conventional CMF in Primary Breast Cancer Patients with Negative Nodes and Estrogen-Receptor-Negative Tumors Specific Aims The objective of this study is to determine whether six cycles of conventional cyclophosphamide, methotrexate and 5-fluorouracil (CMF) are as effective with respect to disease-free survival and survival as six cycles of sequential methotrexate and 5-fluorouracil (M→F) followed by leucovorin for negative-node patients whose tumors are estrogen-receptor-negative. |